Prevalence of Trichomonas vaginalis of 5-10% in the general female population, 50-60% in female prison population and commercial sex workers (CSWs) in women who have a complaint at the vagina, the prevalence of Trichomonas vaginalis between 18-50%, and at 30-50 % of women with gonorrhea were also found in Trichomonas vaginalis infection. Prevalence of Trichomonas vaginalis infection in men attending sexually transmitted disease clinic as much as 6%. Trichomonas vaginalis infection in men is always associated with non-gonorrhea urethritis, with prevalence between 1-68%.
Treatment of vaginal trichomoniasis is not as easy as a direct relationship between the susceptibility of organisms to metronidazole at a dose of medication, but may depend on a complex interaction of several factors which include: drug susceptibility of Trichomonas, the local drug concentration, redox potential intravagina (which may regulate the amount of drugs taken by the parasite) and the accompanying vaginal microflora (which may reduce the number of local drug). But metronidazole is still the drug of choice for trichomoniasis in women and men. There is no effective alternative treatment in addition to metronidazole.
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